Install with brew
Use brew to install the nginx with command:

$ brew install nginx

After install run:

$ sudo nginx

The default place of nginx.conf on Mac after installing with brew is:

/usr/local/etc/nginx/nginx.conf

Changing the default port
The nginx default port is 8080, we shall change it to 80. First stop the nginx server if it is running by:

$ sudo nginx -s stop

Then open nginx.conf with:

$ vim /usr/local/etc/nginx/nginx.conf

server {
        listen 80;
        server_name love.samleslie.com;

        root /home/dingsai/piu;
        index index.html;
}

server {
    listen 80;
    server_name blog.samleslie.com;
    root /home/dingsai/blog/my_blog;

    location /static/{
        alias /home/dingsai/blog/my_blog/static/;
    }
    location / {
        include uwsgi_params;
        uwsgi_pass 127.0.0.1:8081;
    }
}